Ji-Hoon Kim1, 2, Young-In Chung3, Jung Sub Lee2, 4, In-Joo Kim2, 5, Yong-Ki Kim2,5, Seong-Jang Kim2, 5

1Division of Child-Adolescent Psychiatry, Department of Psychiatry, Pusan National University School of Medicine, Yangsan-si, Gyeongnam, Republic of Korea
2Medical Research Institute, Pusan National University School of Medicine, Yangsan-si, Gyeongnam, Republic of Korea
3Department of Psychiatry, Pusan National University School of Medicine, Yangsan-si, Gyeongnam, Republic of Korea
4Department of Orthopedic Surgery, Pusan National University School of Medicine, Yangsan-si, Gyeongnam, Republic of Korea
5Department of Nuclear Medicine, Pusan National University School of Medicine, Yangsan-si, Gyeongnam, Republic of Korea

摘要：基于感兴趣区方法进行的正电子发射计算机断层扫描研究有其局限性：由于是视觉分析，其可靠性较差，且其能检测到的脑区也有限。我们应用基于统计参数图的方法对14例注意缺陷多动障碍患儿与15例脑代谢正常的脊柱侧凸患儿静息态的18F-氟代脱氧葡萄糖-正电子发射计算机断层扫描脑扫描结果进行比较分析。发现注意缺陷多动障碍患儿的左海马旁回、左海马、左带状前回、右小脑前后叶、左颞上回、左岛叶、左额内侧和中回、右额内侧回、左基底节葡萄糖代谢水平均下降。实验提示注意缺陷多动障碍的发病不是只与某一特定脑区功能失调有关。

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